core sensing from Darmstadt develops an innovative sensor technology that uses smart sensors inside mechanical components in combination with intelligent algorithms to provide valuable insights into machines, plants and commercial vehicles. This allows them to be digitized and thus operated more efficiently, potential problems to be detected at an early stage, expensive scrap and downtime costs to be avoided, and new digital business models to be implemented.
Avelo is a Zurich-based diagnostics startup developing a simple breath collector to improve the diagnosis of tuberculosis and other respiratory infections that cause pneumonia – the fourth leading cause of death worldwide. The breath collector will enable non-invasive and painless samples, particularly from the lower respiratory tract, which can be analyzed with existing PCR testing infrastructure.
Invasight is a preclinical biotech startup specialised in oncology, which is focussed on the development of targeted therapies with less side effects for patients with invasive cancers. The core technology of the company is a proprietary screening platform, which enables the development of specific protein-protein interaction antagonists (PPIAs). The lead project is a novel FGFR pathway inhibitor for the treatment of various invasive cancers.
mk2 is a Munich-based biotechnology company specializing in the development, production and research of peptides. The basis for this is a revolutionary technology platform, which enables the scalable and thus cost-effective synthesis of peptides of the highest quality and purity. With the help of this technology, authentic peptides with any physical and chemical properties can be synthesized.
hemotune is developing a unique approach to extracorporeal blood purification. The HemoSystem platform technology uses magnetic nanoparticles to selectively remove previously inaccessible biomolecules from the blood. Initially, the method is to be used primarily in cases of an uncontrolled immune reaction (septic shock). In addition, the platform can also be used for a variety of other indications.
Tubulis uses proprietary technologies to develop novel drugs whose mechanisms of operation address the deep-seated causes of the respective disease. The goal is to expand the therapeutic potential of Antibody Drug Conjugates (ADCs) to enable more targeted and effective treatment of cancer and other diseases.
Code Intelligence enables software security testing through innovative fuzzing already in the development phase. Using CI Fuzz, vulnerabilities can be detected earlier and fully automatically, so that developers can analyze bugs faster and fix them at the code base. CI Fuzz thus drastically improves software stability and reliability.
Algiax Pharmaceuticals researches and develops innovative products for the treatment of diseases with high unmet medical demand. The core of the development is AP-325, a low-molecular GABAA receptor modulator, which is currently in clinical development as a therapy for neuropathic pain.
Thermosome develops drug candidates based on its proprietary technology platform for thermosensitive liposomes (TSL). TSLs are heat-inducible nanocarriers for local and targeted drug delivery that can achieve up to 15 times higher local drug concentrations. The aim is to improve the treatment of localized diseases such as tumors.
iThera Medical develops optoacoustic imaging systems for preclinical research and clinical diagnostics. Optoacoustics uses the photoacoustic effect – absorption of laser light in tissue generates an ultrasound signal – the analysis of which, without invasive intervention, provides information on a wide range of indications, such as cancer or inflammatory diseases.
Resistell is developing a technology for quicker, more precise antibiotic susceptibility testing. After bacteria have been exposed to antibiotics, their effect can be demonstrated by the changing movement of bacterial cells. In comparison to a culture-based antibiogram, this method provides results within a few hours. This allows patients to receive the right medication in the right concentration, from day one.
adivo is developing a technology platform for the selection of species-specific therapeutic antibodies for use in veterinary medicine. These antibodies have pre-defined characteristics that allow the generation of lead candidates with optimal functionality for dogs and other animals.
Implandata Ophthalmic Products (IOP) designs, produces and distributes disruptive solutions for ophthalmology, particularly for glaucoma patients. The CE-approved eyemate® system combines state-of-the-art medical technology with digital health solutions and therefore enables more efficient therapy and disease management.
advanceCOR develops innovative medications for the treatment of cardiovascular diseases. At the heart of this research and development is Revacept®, a therapeutic agent in clinical development for the treatment of acute arterial thromboses and thromboembolism.
4tiitoo develops a framework for Natural User Interfaces (NUIA), which can be used in all applications and which allows controlling the computer using eyes, gestures and speech. As a result, workplaces can be designed more productively and employees can accomplish their tasks more efficiently, safely and with fewer ergonomic restrictions.
Lunaphore is developing an immunohistochemical testing procedure that uses microfluidic systems to achieve faster, more precise analysis of tumor tissue. In addition, Lunaphore enables digital pathology by integrating imaging systems such as a microscope with sequential data extraction.
InSphero offers advanced yet easy-to-use tissue-based 3D assay solutions for predictive drug classification to bring more reliable, effective drugs to the market faster. The core of the solution are the physiologically relevant 3D InSight™ platforms and associated microchip technologies.
Versantis developed drugs and diagnostics for the treatment of acute and chronic liver failure with the aim of revolutionizing previous standards of care. The lead project VS-01 was in pre-clinical phase 2 at exit with the potential to become a first-line therapy for chronic liver failure. Versantis was acquired by GENFIT in September 2022 to jointly continue the development of its revolutionary therapeutics.
GNA Biosolutions developed a disruptive PCA (Pulse Controlled Amplification) technology for DNA analysis from complex clinical samples. GNA’s technology delivers results within a few minutes and is therefore significantly faster and cheaper than other solutions in the field of molecular diagnostics. GNA’s rapid tests are also used for the diagnosis of COVID-19.
cunesoft developed an innovative software platform for the pharmaceutical industry’s regulatory processes, which leads to more efficient processes and thus to easier and faster drug approval. In early 2020, the company exited to Phlexglobal, a leading provider of technologies and services in the clinical and regulatory area.
kooaba developed an augmented reality technology platform for image recognition on mobile devices. By enriching it with additional information about the identified object, an exciting combination of the physical world with digital content is created. In 2014, kooaba was acquired by Qualcomm, one of the world’s largest semiconductor manufacturers and suppliers of products for mobile communications.